King Henry VIII's Madness Explained





Could a genetic disorder and a rare blood type explain Henry VIII's health problems, his wives' miscarriages, and even his madness?

Among a long list of personality quirks and historical drama, Henry VIII is known for the development of health problems in mid-life and a series of miscarriages for two of his wives. In a new study, researchers propose that Henry had an X-linked genetic disorder and a rare blood type that could explain many of his problems.

By suggesting biological causes for significant historical events, the study offers new ways to think about the infamous life of the notorious 16th-century British monarch, said Catarina Whitley, a bioarchaeologist who completed the research while at Southern Methodist University.

Plenty of historians have written about Henry's health problems. As a young man, he was fit and healthy. But by the time of his death, the King weighed close to 400 pounds. He had leg ulcers, muscle weakness, and, according to some accounts, a significant personality shift in middle age towards more paranoia, anxiety, depression and mental deterioration.

Among other theories, experts have proposed that Henry suffered from Type II diabetes, syphilis, an endocrine problem called Cushing's syndrome, or myxedema, which is a byproduct of hypothyroidism.

All of those theories have flaws, Whitley said, and none address the monarch's reproductive woes. Two of his six wives -- Ann Boleyn and Katherine of Aragon -- are thought to have suffered multiple miscarriages, often in the third trimester....


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